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Olumacostat glasaretil
CAS No. 1261491-89-7
Olumacostat glasaretil ( Olumacostat glasaretil; DRM01B; DRM-01B )
产品货号. M11083 CAS No. 1261491-89-7
A small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥494 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1191 | 有现货 |
|
| 25MG | ￥2260 | 有现货 |
|
| 50MG | ￥3872 | 有现货 |
|
| 100MG | ￥5646 | 有现货 |
|
| 200MG | ￥8035 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Olumacostat glasaretil
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes.
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产品描述A small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes; reduces saturated and monounsaturated fatty acyl chains across lipid species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters; significantly reduces hamster ear sebaceous gland size; a pro-drug of TOFA with enhance delivery in vivo.Other Indication Phase 3 Clinical
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同义词Olumacostat glasaretil; DRM01B; DRM-01B
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number1261491-89-7
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分子量481.62
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分子式C26H43NO7
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESO=C(C1=CC=C(OCCCCCCCCCCCCCC)O1)OCC(N(CC(OCC)=O)C)=O
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化学全称2-Furancarboxylic acid, 5-(tetradecyloxy)-, 2-[(2-ethoxy-2-oxoethyl)methylamino]-2-oxoethyl ester
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Bissonnette R, et al. J Am Acad Dermatol. 2017 Jan;76(1):33-39.
2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
产品手册
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